Biological processes are shaped by changes across multiple molecular layers, including RNA and proteins, with no single layer ...

In a recent study published in Nature Communications, a team of researchers at the Carl R. Woese Institute for Genomic Biology reports a new, robust computational toolset to extract biological ...

A consensus machine learning approach integrating single-cell and spatial transcriptomics identifies nucleolin (NCL) as a ...

A Nature Methods benchmark of 11 segmentation methods across 15 spatial transcriptomics datasets shows that algorithm and ...

Spatial transcriptomics has transformed brain research by preserving single-cell molecular resolution within intact tissue coordinates. The brain, organized across cortical layers, long-range ...

Spatial transcriptomics now spans two fundamentally different measurement strategies, and the choice between them shapes every downstream result a lab will generate. Sequencing-based platforms capture ...

Together, the findings describe human urogenital development as a coordinated multi-organ process at the levels of chemical ...

Knowing the location of a gene within intact tissue or a single cell allows scientists to unlock unknown cellular functions. This information is often lost in most genetic sequencing techniques, but ...

A lung affected by deadly forms of COVID-19 not only loses essential cells for breathing but also undergoes profound changes in its internal organization and the way its cells communicate with each ...