Biological processes are shaped by changes across multiple molecular layers, including RNA and proteins, with no single layer ...

In a recent study published in Nature Communications, a team of researchers at the Carl R. Woese Institute for Genomic Biology reports a new, robust computational toolset to extract biological ...

A consensus machine learning approach integrating single-cell and spatial transcriptomics identifies nucleolin (NCL) as a ...

Spatial transcriptomics has transformed brain research by preserving single-cell molecular resolution within intact tissue coordinates. The brain, organized across cortical layers, long-range ...

A Nature Methods benchmark of 11 segmentation methods across 15 spatial transcriptomics datasets shows that algorithm and ...

Spatial transcriptomics now spans two fundamentally different measurement strategies, and the choice between them shapes every downstream result a lab will generate. Sequencing-based platforms capture ...

Together, the findings describe human urogenital development as a coordinated multi-organ process at the levels of chemical ...

Knowing the location of a gene within intact tissue or a single cell allows scientists to unlock unknown cellular functions. This information is often lost in most genetic sequencing techniques, but ...

A lung affected by deadly forms of COVID-19 not only loses essential cells for breathing but also undergoes profound changes in its internal organization and the way its cells communicate with each ...