Spatial transcriptomics now spans two fundamentally different measurement strategies, and the choice between them shapes every downstream result a lab will generate. Sequencing-based platforms capture ...
Spatial transcriptomics has transformed brain research by preserving single-cell molecular resolution within intact tissue coordinates. The brain, organized across cortical layers, long-range ...
Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...
A Nature Methods benchmark of 11 segmentation methods across 15 spatial transcriptomics datasets shows that algorithm and ...
A novel spatial transcriptomics atlas developed by Northwestern Medicine scientists may improve the understanding of niche cellular interactions in the gastrointestinal tract that promote the ...